What happens when you over eat and gain weight

If you are overfed,then your cells will be too-and overfed cells don’t work properly.When you take in more food than you need, levels of the hormones insulin and leptin rise in the body and send a barrage of messages to the cells, telling them to grow and produce lots of new cells. But when cells are putting all their efforts into growth and producing new cells, the lysosomes work less efficiently and the essential maintenance gets neglected, so waste builds up and damage fails to get repaired, Dr. Ismail Khadi of Kiemba Clinic say.

He added, if this happened to your car it might carry on functioning for a while, but it wouldn’t be long before it was off the road.When it happens in your body and you have increasing numbers of poor quality cells that are not repairing damage and getting rid of waste, it becomes the starting point for many diseases,including cancer.

Over eating is also bad news for your cell’s power plant – the mitochondria.They decline in number, become damaged and stop producing protective antioxidants. Like a worn-out battery, they start to leak harmful ‘oxidising’ substances,which can demage the cells and surrounding tissues.This damage causes inflammation, which if unchecked can lead to cancer, heart disease and diabetes.

As well as overfed cells becoming dysfunctional because of the barrage of signals they receive from hormones, overeating actually triggers certain genes in the cell to be switched on and others to be switched off.A recent study found that just five days of feeding healthy young men with a high-fat, high calorie diet caused detrimental changes to their cells, by switching on genes associated with inflammation and cancer.By contrast,other studies have shown that eating less and eating the right sort of foods, one example being resveratrol, the protective antioxidant found in fruits (especially grapes) and peanuts, can actually reverse these damaging changes and ‘switch off’ the harmful genes.

What is playing out in your cells when you overeat is similar to what happens to your as you get older so eating more than your body needs effectively speeds up the clock and ages you prematurely.

According to research studies, why weight matters. Being owerweight increases the risk of heart disease, stroke, type 2 diabetes, dementia and more than 12 different cancers, including breast cancer,bowel cancer and cancers of  aesophogus (gullet), thyroid gland,kidney,womb,gall bladder,pancreases, malignant melanoma and cancers of the blood and immune systems, such as leukemia, maltiple myeloma, and non-Hodgkins lymphoma.

People who are overweight are more likely to suffer from arthritis,indigestion,gallstones,stress, anxiety,depression, infertility and sleep problems.

Being very overweight (3 stone/19 kg above your healthy weight) is as harmful to health as smoking and can reduce life expectancy by seven years.If you are very overweight and also smoke it can shorten your lifespan by 14 years.

Being overweight limits healthy life expectation.In the Uk women live, on average, to the age of 82, but their good health only lasts untill their mid 60s, while men live to 78, with good health until the age of 64 often due to weight related illness.

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